Mary-Claire King, PhD
Department of Medicine, Genome Sciences
Dr. King’s discovery has transformed the diagnosis, drug development, and treatment of inherited breast and ovarian cancer. The identification of BRCA1 — and subsequently BRCA2 — has made it possible to diagnose whether a woman in an affected family is at extremely high risk of developing breast and ovarian cancer, enabling her to pursue preventative treatment.
King’s passion for gene discovery integrated tools from genetics, statistics, mathematics, epidemiology, molecular biology, genomics and clinical medicine. Her revolutionary approach to gene discovery has had an impact on many other diseases, ranging from prostate cancer to inherited hearing loss to schizophrenia. King is also a pioneer in the development of DNA sequencing for the identification of victims of human rights’ violations.